If your dentures require a large amount of adhesive on a regular basis, it may be causing harmful side effects, and it is advised that you discontinue their use, consult with your dentist or doctor, and use a zinc free alternative. Dentures should hold good suction without the use of adhesives, and if used, only a drop the size of a pencil eraser should be used. If you have had your dentures for many years, and they don’t seem to fit as well without adhesive, consult your dentist because it may be time to have your dentures re-lined, or re-made to eliminate the need for messy and potentially harmful adhesives.